The Suh Lab

Functional Genomics of Human Aging & Longevity

Columbia University Irving Medical Center
Department of Obstetrics and Gynecology
Department of Genetics and Development

Welcome!

The Suh Lab has been taking human genetics and functional genomics approaches to understand the fundamental mechanisms of aging in humans. Aging is the single largest risk-factor for most chronic diseases such as Alzheimer’s disease, cancer, cardiovascular disease, type 2 diabetes, etc. and is emerging as a major component in basic, translational and clinical research. Our long-term research goals are to investigate the genetic component that underlies the interface between intrinsic aging and disease.

Geroscience Hypothesis

Since aging is the greatest risk factor for most chronic ailments, target aging will prevent, delay, and even reverse most human diseases.

Main Research Questions:

  1. Can we identify (epi)genetic signatures of “geroscience” in humans?

  2. What are the fundamental mechanisms of aging underlying geroscience in humans?

  3. Can we apply geroscience to promote healthspan and lifespan in humans?

Genetics of Aging, Aging-related Diseases, and Longevity

Suh Lab in the NEWS

Upcoming talks

Past talks in 2023